Today marks the 4th observance of World Psoriasis Day. The purpose is to increase awareness of this genetic immune system disease which affects 7.5 million people in the U.S. and 125 million people around the world. Psoriasis is a non-contagious skin condition that can lead to other serious conditions, including heart disease, diabetes, liver [...]
Etanercept, marketed under the name Enbrel, is a drug that belongs to the class of drugs known as tumor necrosis factor (TNF)-alpha blocker. It is used primarily to treat rheumatoid arthritis, but has also been approved for use in treating polyarticular juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, and psoriasis.
Psoriasis is a genetic disease with at least eight chromosomes so far that researchers have identified as being connected to the genetic transmission of the disease. There are also several environmental factors that play key roles in the development of psoriasis, among them are drugs, skin trauma, infection and stress. [...]
I have posted in the past about the links discovered between various forms of arthritis and genetics. Here are a couple more genes that have been identified with an increased risk in arthritis.
HLA-B27
The first gene, HLA-B27, was determined in the 1960’s to have a link with spondyloarthropathies, which are a group of [...]
The first international guidelines for the treatment of psoriatic arthritis has been developed and published by a group of rheumatologists, dermatologists, and patient advocates. [...]
A research team led by scientists from the University of Michigan and the University of Utah School of Medicine have identified four new DNA “hotspots” that increase the risk of psoriasis. [...]