Etanercept, marketed under the name Enbrel, is a drug that belongs to the class of drugs known as tumor necrosis factor (TNF)-alpha blocker. It is used primarily to treat rheumatoid arthritis, but has also been approved for use in treating polyarticular juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, and psoriasis.
Psoriasis is a genetic disease with at least eight chromosomes so far that researchers have identified as being connected to the genetic transmission of the disease. There are also several environmental factors that play key roles in the development of psoriasis, among them are drugs, skin trauma, infection and stress. [...]
Rheumatoid arthritis (RA) is an auto-immune disease marked by inflammation of the joints and surrounding tissue. Psoriatic arthritis is a condition related to psoriasis, a chronic skin condition that is also an auto-immune disease. Psoriatic arthritis is usually confined to the knees, ankles, and joints in the feet.
Treatment for psoriatic arthritis has generally [...]
I have posted in the past about the links discovered between various forms of arthritis and genetics. Here are a couple more genes that have been identified with an increased risk in arthritis.
HLA-B27
The first gene, HLA-B27, was determined in the 1960’s to have a link with spondyloarthropathies, which are a group of [...]
The first international guidelines for the treatment of psoriatic arthritis has been developed and published by a group of rheumatologists, dermatologists, and patient advocates. [...]
A research team led by scientists from the University of Michigan and the University of Utah School of Medicine have identified four new DNA “hotspots” that increase the risk of psoriasis. [...]