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Savient Pharmaceuticals, Inc, has been conducting a clinical trial of its experimental gout treatment drug Puricase. Puricase is intended for use in patients that have not had success in treatment of their gout with other therapies. The trial included 212 patients, of which 158 completed the randomized trial. The company reported that 19 of [...] Two recent studies have found the high levels of urate, the cause of gout, may slow, or even help prevent, the progression of Parkinson’s disease symptoms. Urate, which is a salt formed from uric acid, is naturally produced in the body. It is known that too much urate can result in problems like gout, [...] A more recent study conducted by researchers in the U.S. and the Netherlands has confirmed the relationship of SLC2A9 with an increased risk of gout. In addition, they also identified 2 additional genes, ABCG2 and SLC17A3, that also appear to increase the risk of gout. In combination, these 3 genetic variations can increase the risk of developing gout by up to 30 to 40 times. [...] A researcher looking at the relationship between gout and heart attacks has discovered that there is a relationship between high uric acid levels and heart failure. Eswar Krishnan, MD, assistant professor of immunology and rheumatology at Stanford University School of Medicine, has conducted a new study looking into just what that relationship is. Uric [...] A new study has shown that there is an inverse relationship between serum uric acid levels and gout, and the risk of parkinson’s disease. [...] Based on the results of recent testing a U.S. Food and Drug Administration (FDA) expert panel has recommended that febuxostat be approved. This would make febuxostat, to be marketed as Uloric, the first gout drug to be approved in over 40 years. [...] The Japanese pharmaceutical, Takeda, has been testing a new drug for use in treating gout. They had applied for approval by the U.S. Food and Drug Administration (FDA) in 2004, but the FDA had requested more data as a result of concerns about a possible increase in heart attack risk. The drug is known [...] |
  
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