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Savient Pharmaceuticals, Inc, has been conducting a clinical trial of its experimental gout treatment drug Puricase. Puricase is intended for use in patients that have not had success in treatment of their gout with other therapies. The trial included 212 patients, of which 158 completed the randomized trial. The company reported that 19 of the patients that [...] Two recent studies have found the high levels of urate, the cause of gout, may slow, or even help prevent, the progression of Parkinson’s disease symptoms. Urate, which is a salt formed from uric acid, is naturally produced in the body. It is known that too much urate can result in problems like gout, however, it does [...] Gout is a painful condition which results from high levels of uric acid in the blood. Over time the uric acid forms crystals in the joints which leads to inflammation, stiffness and pain. Normally, the kidneys remove uric acid from the blood and eliminate it in urine. But the kidneys in those with gout do not keep [...] Gout has typically been treated with non-steroidal anti-inflammatory drugs (NSAIDs). But a report presented at the American College of Rheumatology on October 30, 2007 indicates that a new therapy may provide greater relief than NSAIDs. The research was a trial involving 10 patients with chronic, active, gouty arthritis. They averaged 62 years of age and had gout [...] A more recent study conducted by researchers in the U.S. and the Netherlands has confirmed the relationship of SLC2A9 with an increased risk of gout. In addition, they also identified 2 additional genes, ABCG2 and SLC17A3, that also appear to increase the risk of gout. In combination, these 3 genetic variations can increase the risk of developing gout by up to 30 to 40 times. [...] |
  
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