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A global team of researchers, led by Professor Matthew Brown, from the University of Queensland’s Diamantina Institute for Cancer, Immunology and Metabolic Medicine, has discovered that there is a genetic relationship between ankylosing spondylitis (AS) and Crohn’s disease. The study was published in the current issue of Nature Genetics. AS is a form of [...] A more recent study conducted by researchers in the U.S. and the Netherlands has confirmed the relationship of SLC2A9 with an increased risk of gout. In addition, they also identified 2 additional genes, ABCG2 and SLC17A3, that also appear to increase the risk of gout. In combination, these 3 genetic variations can increase the risk of developing gout by up to 30 to 40 times. [...] British scientists are conducting the first study on the human genome to determine the genetic causes of osteoarthritis. [...] I have posted in the past about the links discovered between various forms of arthritis and genetics. Here are a couple more genes that have been identified with an increased risk in arthritis. HLA-B27 The first gene, HLA-B27, was determined in the 1960’s to have a link with spondyloarthropathies, which are a group of [...] A research team led by scientists from the University of Michigan and the University of Utah School of Medicine have identified four new DNA “hotspots” that increase the risk of psoriasis. [...] The Arthritis Foundation recently came out with its list of the top 10 arthritis events for the year 2007. This series will focus on those events. #4: Identification of RA Susceptibility Genes STAT4 and TRAF1-C5 Genetic researchers have been able to perform evaluations of variations in DNA. One of the areas of research that [...] |
  
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