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Interesting story from New Zealand discussing the possibility that high rates of gout in Pacific Islanders may be a genetic trait passed to them by ancient voyagers across the Pacific Ocean. Dr. Hallie Buckley, from Otago University’s Department of Anatomy and Structural Biology, has been studying bones from the oldest cemetery found in thePacific [...] Like all aspects of the development of the human body, genetics dictate each individual’s height. Last year a team of researchers identified the initial common gene that influences height. That same team has now identified 20 additional genetic regions that can collectively influence height differences of almost 2.5 inches. According to the research team, [...] A study published in the New England Journal of Medicine says that more than 25% of men with hemochromatosis, the most common inherited blood disorder, will develop arthritis, liver cancer and other serious complications. Hemochromatosis is a condition where the body absorbs up to three times the normal amount of iron. Over an extended [...] The genetic connection to many types of arthritis are being discovered at a rapid pace. Now comes findings published in the New England Journal of Medicine of another genetic link rheumatoid arthritis. Two regions on Chromosome 9 have been previously identified as being linked to susceptibility and severity of RA. These are known as [...] Gout is a painful condition which results from high levels of uric acid in the blood. Over time the uric acid forms crystals in the joints which leads to inflammation, stiffness and pain. Normally, the kidneys remove uric acid from the blood and eliminate it in urine. But the kidneys in those with gout [...] Tumor necrosis factor (TNF) has been identified as having a key responsibility in many inflammatory diseases, including rheumatoid arthritis (RA). There has been substantial research into the early signaling pathways activated by TNF, but there is not much known about the delayed and chronic TNF responses. In addition, cells called macrophages (cells within the [...] I have reported here previously about the advances in arthritis genetic research and the hopes that these studies would provide the basis for potential treatment options. Now researchers have reported that clinical studies show that gene therapy reduces rheumatoid arthritis (RA) patient’s symptoms. [...] |
  
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