The FDA ordered that the class of drugs known as TNF blockers carry a warning on the packaging that their use carries the risk of developing a potentially deadly fungal disease called histoplasmosis. [...]
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A global team of researchers, led by Professor Matthew Brown, from the University of Queensland’s Diamantina Institute for Cancer, Immunology and Metabolic Medicine, has discovered that there is a genetic relationship between ankylosing spondylitis (AS) and Crohn’s disease. The study was published in the current issue of Nature Genetics. AS is a form of arthritis that [...] Spondylarthritis (SpA) represents a group of arthritis diseases that have similar symptoms such as inflammatory back pain and inflammation at sites where tendons attach to bone. It includes ankylosing spondylitis, psoriatic arthritis, inflammatory bowel-disease-related arthritis, reactive arthritis and undifferentiated spondylarthritides (uSpA). Since Chlamydia trachomatis or Chlamydia pneumoniae frequently cause reactive arthritis, a new study led by [...] Etanercept, marketed under the name Enbrel, is a drug that belongs to the class of drugs known as tumor necrosis factor (TNF)-alpha blocker. It is used primarily to treat rheumatoid arthritis, but has also been approved for use in treating polyarticular juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, and psoriasis. On May 1st, the U.S. [...] I have posted in the past about the links discovered between various forms of arthritis and genetics. Here are a couple more genes that have been identified with an increased risk in arthritis. HLA-B27 The first gene, HLA-B27, was determined in the 1960’s to have a link with spondyloarthropathies, which are a group of diseases that affect [...] |
  
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